Introduction Sulbutiamine is a nootropic (cognitive enhancer) and a man-made version of vitamin B Thiamine, developed by Japanese researchers in the 1960s. In contrast to Thiamine, it easily dissolves in fats, and not in water. It was developed to curb the Thiamine deficiency of the Japanese. Sulbutiamine aims to improve the levels of Thiamine in the brain for greater mental health. It is used to treat asthenia (fatigue) in patients, though it may be useful…